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Humann

Neo40 Pro

Neo40 Pro

Neo40® is our flagship Nitric Oxide product, clinically shown to support healthy blood pressure, circulation and energy. Backed by six peer-reviewed, randomized, placebo-controlled trials, Neo40® features a patented, dual-action formula that helps quickly restore and sustain Nitric Oxide levels. It’s the most scientifically studied Nitric Oxide lozenge—and recommended by thousands of healthcare professionals.

Read more about this product

Neo40® is our flagship Nitric Oxide product, clinically shown to support healthy blood pressure, circulation and energy. Backed by six peer-reviewed, randomized, placebo-controlled trials, Neo40® features a patented, dual-action formula that helps quickly restore and sustain Nitric Oxide levels. It’s the most scientifically studied Nitric Oxide lozenge—and recommended by thousands of healthcare professionals.

Read less about this product
Tablet 60
How to Use
Place one tablet in your mouth and let it dissolve. We recommend an initial Nitric Oxide restoration loading period. During the first 30 to 45 days, take one tablet two times a day, or every 12 hours. This could be one in the morning and one in the evening.

Beetroot from non-GMO beetroot powder that helps supports Nitric Oxide production through the nitrate-nitrite pathway.

Hawthorn Berry Extract contains high levels of antioxidants (polyphenols) that help activate the key enzyme eNOS, which helps your body quickly convert L-arginine to Nitric Oxide. It also helps reduce nitrite to Nitric Oxide.

5-MTHF (5’-Methyltetrahydrofolic acid) is used in the synthesis of BH4. Maintaining sufficient levels of this very important co-factor is necessary for proper function of eNOS. If the level of tetrahydrobiopterin is not maintained, the enzyme becomes uncoupled and generates free radicals rather than Nitric Oxide.

Sodium Nitrite is quickly converted to Nitric Oxide by hawthorn berry extract and has clinically significant vasodilator activity.

L-citrulline is an effective substitute source for L-arginine, which eNOS converts to Nitric Oxide. It also inhibits arginase, which removes L-arginine from circulation. This then reduces Nitric Oxide production.

Vitamin B12 reduces direct inhibition of eNOS by homocysteine and production of ADMA (asymmetrical dimethyl-arginine), and helps replenish tetrahydrobiopterin.

Vitamin C helps prevent removal of Nitric Oxide by free radicals and removes free radicals that inhibit eNOS.

  • cardiovasular
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Frequently Asked Questions

Are your supplements third-party tested and manufactured safely?

Yes, our supplements are third-party tested, GMP verified, made in FDA-regulated facilities, and responsibly sourced to ensure top-tier quality, safety, and sustainability.

How do I know which supplements are right for me?

We recommend speaking with a licensed healthcare provider or using our personalized supplement quiz to find products tailored to your individual health needs.

Are your products safe for children or during pregnancy?

Some products may be suitable, but please consult your healthcare provider before use, especially for children or during pregnancy or breastfeeding.

Do you offer subscriptions or auto-ship options?

Yes! We offer easy subscription and auto-ship options with exclusive discounts, so you’ll never miss a dose of your essentials.

What Makes Functional Medicine Special

  • FMI Doctor Approved

  • Confirmed Quality & Purity

  • Third-Party Tested

  • Made at FDA Regulated Facilities